6.Microbubble dynamics under the effect of an acoustic field

We study the microbubble dynamics in a liquid (blood) confined within an elastic solid (blood vessel) under the effect of an external acoustic field. Ultrasound-mediated microbubble technology has been used for various therapeutic applications, including the breakup of urinary stones, diagnostic imaging, and gene delivery. Recent advancement in ultrasound is using microbubble oscillation to enhance the effect of the drug in chemotherapy. Due to the volume oscillations of the microbubbles under the effect of an acoustic field (Figure xxx), the permeability of blood vessels is temporarily increased, which increases the uptake of drugs into cells.

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References

  • Kaykanat, S.İ. and A. K. Uguz 2023 The Role of Acoustofluidics and Microbubble Dynamics for Therapeutic Applications and Drug Delivery Biomicrofluidics, 17(2) 021502 1-19 (DOI: https://doi.org/10.1063/5.0130769)

General references

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